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Clinical Articles / BY: John H. Hay, MB July/August 2003
... traditional approach to adjuvant treatment of stage II (node-negative tumors that penetrate into the perirectal fat) and stage III (node-positive tumors) rectal cancer in North America is ... should be smaller. Surgery is recommended in the 6- to 10-week period after the completion of radiation, before any ...
Clinical Articles / BY: P. Terry Phang, MD September 2003
... with the lowest published recurrence rates—5% to 10%—for rectal cancer management. [1-4]  Surgeon awareness ... more nodes was required to assure accuracy of a metastatic node-negative stage. [9] The main aim of this study is to ... tumor to radial margin. • Minimum distance from lymph node to circumferential margin. • Lymphatic or vascular ...
Clinical Articles / BY: P. Terry Phang, MD September 2003
... resection was performed in 29% of cancers located 5 cm to 10 cm from the anus in the midrectum. Adequacy of resection ... to nine rectal cancer operations; 18 hospitals performed 10 or more rectal cancer operations. A total of 145 surgeons ... lymph nodes to determine that there are no regional lymph node metastases. [14,15]  However, the average number of ...
Clinical Articles / BY: C.J.H. van de Velde, MD, PhD, FRCS, FRCPS September 2003
... are of major importance in achieving local control, [10]  standardization and quality control with respect to ... significant in patients who had lesions located more than 10 centimetres from the anal verge and in patients with TNM ... to safety margins, excision of the mesorectum, and lymph node dissection. Currently, global local recurrence rates of ...