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Premise / BY: Paula B. Gordon, OBC, MD, FRCPC, FSBI May 2023
... meta-analysis shows mortality reduction of only 15% to 20%. Although the studies have now been discredited, CNBSS-1 ... And most of those cancers are small, invasive, and node negative. In addition to the risk of masking cancer, ... Vancouver study, the average tumor size was 9 mm, all were node negative, the biopsy rate was 1.3%, and the positive ...
Clinical Articles / BY: David F. Schaeffer, MD, FRCPC July/August 2023
... the submucosa (T1) is associated with low rates of lymph node metastases and excellent outcomes. A subset of patients ... through the muscularis mucosae, there is no risk for lymph node metastasis. Therefore, as per the BC Colon Screening ... controlling for surveillance colonoscopies.[ 15-20 ] In addition, several studies have shown a reduced risk ...
Clinical Articles / BY: Paul J. Oxley, MD, FRCSC April 2021
... It is defined as a slowing of the heart rate by more than 20% from baseline following globe manipulation or traction of ... motor response, which causes impulses to the sinoatrial node and triggers a slowing of the heart rate. The most ...
Clinical Articles / BY: Julian Marsden, MD May 2019
... in a community with a population of less than 10 000.[ 20 ] In order to minimize bias, EM Network Management Team ... in its early phase of development. Each urban and rural node represents an ED or diagnostic and treatment centre with ... in the diagram does not signify value, the size of each node does. The larger the node the more value respondents ...
Clinical Articles / BY: Colin Mar, MD, FRCPC December 2019
... size, whether less than or more than 15 mm, and lymph node involvement (Objective 4). The 2011 to 2015 data ... to provide estimates using some of these factors.[ 19 , 20 ] Using single factors to predict risk is further ... density on prognostic factors such as tumor size and lymph node involvement (Objective 4). The 2011 to 2015 data ...
Editorials / BY: Rona E. Cheifetz, MD, MEd, FRCSC, FACS March 2018
... a greater range of reconstructive options. Axillary lymph node surgery has also evolved, with sentinel lymph node biopsy being recommended for most patients with a ... an improvement in outcomes for breast cancer over the past 20 years with more individualized and multimodal treatment ...
Clinical Articles / BY: F. Michelle Sutter, MD, FRCSC March 2018
... is not necessary after mastectomy for DCIS. Invasive node-negative breast cancer   In general, adjuvant ... whole-breast radiation is recommended for patients with node-negative disease who have undergone BCS as this approach ... therapy is delivered in an accelerated fashion over 16 to 20 sessions. Depending on patient factors such as large ...
Clinical Articles / BY: Connie G. Chiu, MD, FRCSC March 2018
... The estimated risk for patients undergoing axillary lymph node dissection (ALND) is 20%, compared with 5% for sentinel lymph node biopsy (SLNB).[ 1 ] However, a more clinically ...
Clinical Articles / BY: Christine E. Simmons, MD, MSc, FRCPC March 2018
... largely accepted as the standard of care in patients with node-positive or high-risk node-negative breast cancer.[ 3 ] Currently, guidelines ... ER-positive and HER2-negative, 35% were HER2-positive, and 20% were triple-negative. While there has been a trend toward ...
Clinical Articles / BY: Rebecca Warburton, MD, FRCSC March 2018
... detrimental to cosmesis.[ 17,18 ] Reoperation occurs in 20% to 30% of BCS cases.[19] Local in-breast recurrence after ... all patients with invasive breast cancer. Axillary lymph node dissection (ALND) has now been replaced by sentinel lymph node biopsy (SLNB) for most patients with clinically ...