Colorectal cancer linked to bacteria

Issue: BCMJ, vol. 53 , No. 10 , December 2011 , Pages 525 News

Two new studies, one of them in­volving Simon Fraser University research­ers, have uncovered the first link between human colorectal cancer and a specific microorganism. 

The studies, just published on­line in the journal Genome Research, found the bacterium Fusobacterium hundreds of times more prevalent in tumors than normal tissue in 99 colorectal cancer patients. 

Fusobacterium is a known infectious agent that is rarely found in the contents of a normal gut. It has not previously been associated with cancer, and it has yet to be proven whether Fusobacterium infection causes or precedes colorectal tumors. 

Researchers plan to further in­vestigate the possibility that Fuso­bac­terium could be a direct cause of colon cancer, and if so, by what mechanism. The same methodology can then be applied to look for correlations be­tween infectious agents in other types of cancer. Some other cancers known to be caused by viruses or bacteria are cervical cancer (human papilloma virus) and liver cancer (hepatitis B and C virus).

. Colorectal cancer linked to bacteria. BCMJ, Vol. 53, No. 10, December, 2011, Page(s) 525 - News.



Above is the information needed to cite this article in your paper or presentation. The International Committee of Medical Journal Editors (ICMJE) recommends the following citation style, which is the now nearly universally accepted citation style for scientific papers:
Halpern SD, Ubel PA, Caplan AL, Marion DW, Palmer AM, Schiding JK, et al. Solid-organ transplantation in HIV-infected patients. N Engl J Med. 2002;347:284-7.

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