Mitochondrial disease clinical manifestations: An overview

CONTENT

General characteristics

Clinical manifestations

Central nervous system

Visual system and auditory system

Neuromuscular system

Cardiovascular system

Gastrointestinal system

Endocrine system

Case examples

Subacute necrotizing encephalopathy (Leigh syndrome)

Cardiomyopathy and conduction defects

Seizures

Visual symptoms

Stroke and stroke-like episodes

Exertional myalgia

Conclusions

Competing interests

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DISCUSSION

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